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Carl Fink's avatar

"The best that a booster can offer us is a restoration of effectiveness, gaining back about 10% efficacy."

Why do you say that? Have you seen a study indicating that? Because I see no obvious reason that it would not increase efficacy beyond the original two-dose regimen, especially if you change to a different vaccine for the booster. (There have been studies showing that using different first and second doses produces better antibody and t-cell response than two of the same agent.)

I agree with your conclusion, which I agree is obvious, but that one sentence puzzles me.

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