4 Comments
Mar 31, 2021Liked by John Skylar, PhD

Glad to hear you're getting vaccinated. I got the Pfizer vaccine this past Friday, and had only minor side effects, headache and a bit of malaise. Acetaminophen was enough to deal with them.

I didn't get a choice at all. I might have preferred J&J, because it has decent data supporting it working against the 351 variant effectively, but I expect the Pfizer vaccine does, too, I just haven't seen any data.

My hope is that as Novavax and others come online, more of the J&J output can be diverted to poor countries, or really, poor regions in general. (That is, J&J might be ideal for rural areas of South Dakota, not just other countries.) Aside from my being a nice person (and I am), it has selfish benefits because we don't need billions of people breeding variants in their bodies.

Then again, Cuba claims that at least one of its vaccines will be storable at room temperature, and also is working on a nasal spray vaccine. Who knows how seriously to take all this?

https://www.washingtonpost.com/world/2021/03/29/cuba-coronavirus-vaccine-iran-venezuela/

https://www.npr.org/sections/goatsandsoda/2021/03/25/980789381/cubas-revolutionary-dream-making-its-own-covid-vaccine

Be well.

Expand full comment
Mar 31, 2021Liked by John Skylar, PhD

With stories about trials in children coming out, I had a question about how they work. Are they looking for efficacy results again? Or mostly making sure its safe for kids? I imagine given the low infection rates in general in little kids the control group won't get that sick regardless, or do they plan on running trials for a really long time to get the data they need?

Expand full comment